The Perry Health Sciences Campus, adjacent to WakeMed's flagship hospital, prepares students for careers in nursing, radiography, dental hygiene and other high-demand health care professions. Wake Tech partners with WakeMed and other local health care institutions to provide hands-on clinical training and Work-Based Learning experiences.

The campus features a state-of-the-art nursing simulation suite, a dental hygiene clinic and an EMS ambulance bay. It is also home to the Wake Early College of Health and Sciences, a partnership with the Wake County Public School System.